The recent passing of acclaimed ghazal singer Pankaj Udhas has drawn attention to pancreatic cancer, shedding light on the importance of recognizing its symptoms and exploring preventive measures. At 72, Pankaj Udhas succumbed to this formidable disease, leaving behind a legacy cherished by many. As we mourn the loss of a beloved artist, it becomes imperative to understand the intricacies of pancreatic cancer, its symptoms, causes, and preventive strategies.

The Last Farewell to Pankaj Udhas

Pankaj Udhas bid his final adieu on a sombre Monday morning, leaving a void in the hearts of his admirers. His daughter, Nayaab Udhas, took to Instagram to share the news of his demise, marking the end of an era in the realm of ghazal music. Anup Jalota, a close friend and fellow musician, expressed his profound grief over the loss, reminiscing about their shared musical journey and the indelible mark left by Pankaj Udhas in the world of music.

Understanding Pancreatic Cancer

Pancreatic cancer manifests as an abnormal growth of cells within the pancreas, an organ nestled behind the lower part of the stomach. This vital organ performs the dual function of producing digestive enzymes and regulating blood sugar levels through hormone secretion.

The predominant form of pancreatic cancer is pancreatic ductal adenocarcinoma, originating from the cells lining the pancreatic ducts responsible for transporting digestive enzymes. Unfortunately, pancreatic cancer often remains undetected until it reaches an advanced stage, as it typically manifests symptoms only after metastasizing to other organs.

Recognizing the Symptoms

According to Dr Uma Dangi, Consultant Medical Oncology, Fortis Hospital, Mulund, symptoms of pancreatic cancer may not manifest until the disease has progressed significantly. However, when they do appear, they may include:

• Persistent abdominal pain radiating to the sides or back.
• Loss of appetite and unintended weight loss.
• Jaundice, characterized by yellowing of the skin and eyes.
• Changes in stool colour and consistency.
• Dark-coloured urine.
• Pruritus (itching).
• Onset of diabetes or worsening glycemic control.
• Pain and swelling in extremities, possibly indicative of blood clots.
• Fatigue and weakness.

Understanding the Causes

The exact aetiology of pancreatic cancer remains elusive, although certain risk factors have been identified. These include:

• Tobacco use, particularly smoking.
• Type 2 diabetes.
• Chronic pancreatitis, characterized by persistent inflammation of the pancreas.
• Family history of pancreatic cancer or genetic predispositions such as BRCA2 mutations.
• Obesity.
• Advancing age, with most cases diagnosed in individuals over 65.
• Excessive alcohol consumption.

Complications and Preventive Measures

As pancreatic cancer progresses, it may give rise to complications such as:

• Severe weight loss due to increased energy expenditure by cancer cells.
• Jaundice resulting from obstruction of the bile ducts.
• Intense abdominal pain caused by tumour compression on surrounding nerves.
• Bowel obstruction due to tumour encroachment on the small intestine.

Preventive measures and early detection play pivotal roles in managing pancreatic cancer risk. Screening protocols, including imaging tests like MRI and ultrasound, may be recommended for individuals with a high predisposition to pancreatic cancer, such as those with a significant family history or genetic mutations.

Genetic testing can identify inherited DNA alterations associated with pancreatic cancer risk, enabling proactive interventions and surveillance. Lifestyle modifications, such as smoking cessation, weight management, and adopting a balanced diet, contribute to lowering the risk of pancreatic cancer.

Bottomline

In the wake of Pankaj Udhas’s demise, understanding pancreatic cancer becomes paramount. By recognizing its symptoms, understanding its causes, and embracing preventive measures, we strive to honour the legacy of the late Ghazal maestro while safeguarding the well-being of future generations.